Recombinant Mouse Fractalkine protein (Cx3cl1) (Active)

Product Description

Recombinant Mouse Fractalkine protein (Cx3cl1) (Active) is available at Gentaur for Next week Delivery.

Gene Name: Cx3cl1,Cx3c,Fkn,Scyd1

Alternative Names : C-X3-C motif chemokine 1, Neurotactin, Small-inducible cytokine D1,,

Expression Region : 210-150aa

AA Sequence : QHLGMTKCEI MCGKMTSRIP VALLIRYQLN QESCGKRAIV LETTQHRRFC ADPKEKWVQD AMKHLDHQAA ALTKNG

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 8.7 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a cell proliferation assay using human peripheral blood lymphocytes (PBL) is less than 0.5 ?g/ml, corresponding to a specific activity of ? 2000 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (By similarity). Binds to CX3CR1. {ECO:0000250}.

Function : Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 and to integrins ITGAV

Involvement in disease :

Subcellular location : Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Processed fractalkine: Secreted

Protein Families : Intercrine delta family

Tissue Specificity : Highest levels in brain. Lower levels in kidney, heart and lung. Also found in skeletal muscle and testis.

Paythway :

Uniprot ID : O35188