Recombinant Mouse Interleukin-4 protein (Il4) (Active)

Product Description

Recombinant Mouse Interleukin-4 protein (Il4) (Active) is available at Gentaur for Next week Delivery.

Gene Name: Il4,Il-4

Alternative Names : IL-4, B-cell growth factor 1, B-cell stimulatory factor 1, BSF-1, IGG1 induction factor

Expression Region : 21-140aa

AA Sequence : M+HIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 13.5 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered, PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by the dose-dependant prolifiration of Murine HT-2 cells is less then 2 ng/ml, corresponding to a Specific Activity of ? 5 × 105 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.

Function : Participates in at least several B-cell activation processes as well as of other cell types

Involvement in disease :

Subcellular location : Secreted

Protein Families : IL-4/IL-13 family

Tissue Specificity :

Paythway :

Uniprot ID : P07750