Recombinant Mouse Lymphotactin protein (Xcl1) (Active)

Product Description

Recombinant Mouse Lymphotactin protein (Xcl1) (Active) is available at Gentaur for Next week Delivery.

Gene Name: Xcl1,Lptn,Ltn,Scyc1

Alternative Names : C motif chemokine 1, Lymphotaxin, Small-inducible cytokine C1

Expression Region : 22-114aa

AA Sequence : VGTEVLEESS CVNLQTQRLP VQKIKTYIIW EGAMRAVIFV TKRGLKICAD PEAKWVKAAI KTVDGRASTR KNMAETVPTG AQRSTSTAIT LTG

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 10.1 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells is less than 100 ng/ml, corresponding to a specific activity of ? 1.0 ×104 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Chemotactic activity for lymphocytes but not for monocytes or neutrophils.

Function : Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.

Involvement in disease :

Subcellular location : Secreted

Protein Families : Intercrine gamma family

Tissue Specificity : Expressed in activated CD8(+) T cells. In the thymus, expressed by medullary thymic epithelial cells.

Paythway :

Uniprot ID : P47993