Recombinant Mouse Placenta-expressed transcript 1 protein (Plet1)

Product Description

Recombinant Mouse Placenta-expressed transcript 1 protein (Plet1) is available at Gentaur for Next week Delivery.

Gene Name: Plet1

Alternative Names : Antigen mAgK114

Expression Region : 28-218aa

AA Sequence : SDNGSCVVLDNIYTSDILEISTMANVSGGDVTYTVTVPVNDSVSAVILKAVKEDDSPVGTWSGTYEKCNDSSVYYNLTSQSQSVFQTNWTVPTSEDVTKVNLQVLIVVNRTASKSSVKMEQVQPSASTPIPESSETSQTINTTPTVNTAKTTAKDTANTTAVTTANTTANTTAVTTAKTTAKSLAIRTLGS

Sequence Info : Full Length of Mature Protein

Tag Info : N-terminal 6xHis-SUMO-tagged

Theoretical MW : 36.1 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cell Biology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.

Function : Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.

Involvement in disease :

Subcellular location : Apical cell membrane, Lipid-anchor, GPI-anchor

Protein Families :

Tissue Specificity : Present in hair follicle cells and sebaceous gland of skin, ciliated epithelial cells of trachea and bronchial tube, striated portion of submandibular gland, distal convoluted tubule cells of kidney, ciliated epithelial cells of oviduct, medulla of adrenal gland and anterior lobe of pituitary gland. Expressed in keratinocytes of the hair follicle at the trichilemmal zone corresponding to the terminally differentiated outermost suprabasal outer root sheath (ORS), including that of the sebaceous gland duct (SGD) and the directly adjacent upper distal end of the companion layer (CL). Expression is similar in all hair follicle growth stages. Also detected during both the early and late anagen phases above the bulge of stem cells. Expressed at the leading edge of the epidermal wound. Not expressed in the interfollicular epidermis (IFE), inner root sheath (IRS) and hair fiber. Highly expressed in placenta. Detected in mammary and prostate epithelia and in the pancreas (at protein level).

Paythway :

Uniprot ID : Q8VEN2