Recombinant Mouse Thrombopoietin protein (Thpo) (Active)

Product Description

Recombinant Mouse Thrombopoietin protein (Thpo) (Active) is available at Gentaur for Next week Delivery.

Gene Name: Thpo

Alternative Names : C-mpl ligand, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand

Expression Region : 22-195aa

AA Sequence : SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 18.7 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4, with 5% Trehalose

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a cell proliferation assay using human MO7e cells is less than 1.0 ng/ml, corresponding to a specific activity of ? 1.0 × 106 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cancer

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

Function : Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

Involvement in disease :

Subcellular location : Secreted

Protein Families : EPO/TPO family

Tissue Specificity : Found mainly in the liver, kidney and skeletal muscle.

Paythway :

Uniprot ID : P40226