Product Description
Recombinant Rat C-X-C motif chemokine 3 protein (Cxcl3) (Active) is available at Gentaur for Next week Delivery.
Gene Name: Cxcl3,Cinc2
Alternative Names : Cytokine-induced neutrophil chemoattractant 2, Macrophage inflammatory protein 2-alpha/beta, MIP2-alpha/beta
Expression Region : 33-101aa
AA Sequence : RELRCQCLKT LPRVDFENIQ SLTVTPPGPH CTQTEVIATL KDGQEVCLNP QAPRLQKIIQ KLLKSDKSS
Sequence Info : Full Length of Mature Protein
Tag Info : Tag-Free
Theoretical MW : 7.8 kDa
Storage Buffer : Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 50 mM NaCl
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 5-50 ng/ml.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Immunology
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. {ECO:0000250, ECO:0000269|PubMed:8043001, ECO:0000269|PubMed:8607872}.
Function : Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.
Involvement in disease :
Subcellular location : Secreted
Protein Families : Intercrine alpha (chemokine CxC) family
Tissue Specificity :
Paythway :
Uniprot ID : Q10746