Recombinant Rat Cardiotrophin-1 protein (Ctf1) (Active)

Product Description

Recombinant Rat Cardiotrophin-1 protein (Ctf1) (Active) is available at Gentaur for Next week Delivery.

Gene Name: Ctf1

Alternative Names : CT-1,

Expression Region : 1-203aa

AA Sequence : MSQREGSLED HQTDSSFSFL PHLEAKIRQT HNLARLLTKY ADQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSALPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP VPEPVATSAL FTSNSAAGVF SAKVLGLHVC GLYGEWVSRT EGDLGQLVPG GVA

Sequence Info : Full Length

Tag Info : Tag-Free

Theoretical MW : 21.4 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.5 ng/ml, corresponding to a specific activity of ? 2.0 × 106 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.

Function : Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.

Involvement in disease :

Subcellular location : Secreted

Protein Families : IL-6 superfamily

Tissue Specificity : Expressed in the ventricle and atrium of adult rats. Also detected in the lung, kidney, liver, skeletal muscle, stomach and urinary bladder. Not detected in brain, colon, testis, spleen or thymus. Overexpressed in the ventricles in the case of hypertension and hypertrophy.

Paythway :

Uniprot ID : Q63086