Recombinant Rat Fractalkine protein (Cx3cl1) (Active)

Product Description

Recombinant Rat Fractalkine protein (Cx3cl1) (Active) is available at Gentaur for Next week Delivery.

Gene Name: Cx3cl1,Acc1,Fkn,Scyd1

Alternative Names : C-X3-C motif chemokine 1, Neurotactin, Small-inducible cytokine D1,,

Expression Region : 210-150aa

AA Sequence : QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNG

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 8.8 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-10 ng/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.

Function : Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 and to integrins ITGAV

Involvement in disease :

Subcellular location : Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Processed fractalkine: Secreted

Protein Families : Intercrine delta family

Tissue Specificity : Highest levels in brain (neurons). Significant levels in kidney, heart, lung and adrenal gland.

Paythway :

Uniprot ID : O55145