Product Description
Recombinant Rat Lymphotactin protein (Xcl1) (Active) is available at Gentaur for Next week Delivery.
Gene Name: Xcl1,Ltn,Scyc1
Alternative Names : C motif chemokine 1, Small-inducible cytokine C1
Expression Region : 22-114aa
AA Sequence : VGTEVLQESI CVSLRTQRLP VQKIKTYTIK EGAMRAVIFV TKRGLRICAD PQAKWVKTAI KTVDGRASAS KSKAETIPTQ AQRSASTAVT LTG
Sequence Info : Full Length of Mature Protein
Tag Info : Tag-Free
Theoretical MW : 10.0 kDa
Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells is less than 100 ng/ml, corresponding to a specific activity of ? 1.0 ×104 IU/mg.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Immunology
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Chemotactic activity for lymphocytes but not for monocytes or neutrophils. {ECO:0000250}.
Function : Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Involvement in disease :
Subcellular location : Secreted
Protein Families : Intercrine gamma family
Tissue Specificity :
Paythway :
Uniprot ID : P51672