anti- 4EBP1 antibody

Product Description

anti- 4EBP1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma..

Immunogen: eukaryotic translation initiation factor 4E binding protein 1

Synonyms: 4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:200

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab10129(4EBP1 Antibody) at dilution of 1:50

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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab10129(4EBP1 antibody) at dilution of 1:1000

Gene ID: 1978

Research Area: Metabolism

Uniprot ID: Q13541