anti- Adenylosuccinate lyase antibody

Product Description

anti- Adenylosuccinate lyase antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: ADSL(adenylosuccinate lyase) is also named as AMPS, ASase, ASL and belongs to the lyase 1 family. It is an enzyme involved in 2 pathways of purine nucleotide metabolism and catalyzes cleavage of succinyl groups to yield fumarate(PMID:18524658). Defects in ADSL are the cause of adenylosuccinase deficiency(ADSL deficiency). In humans, mutations in ADSL lead to an inborn error of metabolism originally characterized by developmental delay, often with autistic features(PMID:20884265)..The ADSL enzymatic activity is reduced in lymphocytes and red blood cells of the patient with severe psychomotor retardation(PMID:9545543). It has 2 isoforms produced by alternative splicing..

Immunogen: adenylosuccinate lyase

Synonyms: Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF, FC

Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100

Image 1: Immunohistochemistry of paraffin-embedded human liver cancer using FNab00161(ADSL antibody) at dilution of 1:50

Image 2: .

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab00161(ADSL antibody) at dilution of 1:400

Gene ID: 158

Research Area: Metabolism

Uniprot ID: P30566