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Product Description
anti- ALKBH5 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine(m6A) RNA, the most prevalent internal modification of messenger RNA(mRNA) in higher eukaryotes(PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA(in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron(PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export(PubMed:23177736). Required for spermatogenesis(By similarity)..
Immunogen: alkB, alkylation repair homolog 5(E. coli)
Synonyms: ABH5, ALKBH5, FLJ20308, OFOXD, OFOXD1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution: WB: 1:200-1:1000
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab00314(ALKBH5 antibody) at dilution of 1:500
Gene ID: 54890
Research Area: Metabolism
Uniprot ID: Q6P6C2
