anti- ANAPC5 antibody

Product Description

anti- ANAPC5 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a..

Immunogen: anaphase promoting complex subunit 5

Synonyms: ANAPC5, APC5, Cyclosome subunit 5

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat kidney using FNab00387(ANAPC5 antibody) at dilution of 1:50

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Image 4: BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab00387(ANAPC5 antibody) at dilution of 1:1000

Gene ID: 51433

Research Area: Metabolism

Uniprot ID: Q9UJX4