Product Description
anti- AP3B1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals..
Immunogen: adaptor-related protein complex 3, beta 1 subunit
Synonyms: ADTB3, ADTB3A, AP 3 complex subunit beta 1, AP3B1, Beta 3A adaptin, HPS, HPS2, PE
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IF, IP
Recommended dilution: WB: 1:500-1:5000 IP: 1:200-1:2000
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Image 4: mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab00463(AP3B1 antibody) at dilution of 1:500
Gene ID: 8546
Research Area: Metabolism
Uniprot ID: O00203