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Product Description
anti- APOBEC3G antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: DNA deaminase(cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and-independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity also against simian immunodeficiency viruses(SIVs), hepatitis B virus(HBV), equine infectious anemia virus(EIAV), xenotropic MuLV-related virus(XMRV) and simian foamy virus(SFV). May inhibit the mobility of LTR and non-LTR retrotransposons..
Immunogen: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
Synonyms: APOBEC related protein, APOBEC related protein 9, APOBEC3G, ARCD, ARP 9, ARP9, bK150C2.7, CEM 15, CEM15, MDS019
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab00495(APOBEC3G Antibody) at dilution of 1:200
Image 2: Immunofluorescent analysis of MCF-7 cells using FNab00495 (APOBEC3G antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).
Image 3:
Image 4: mouse colon tissue were subjected to SDS PAGE followed by western blot with FNab00495(APOBEC3G Antibody) at dilution of 1:100
Gene ID: 60489
Research Area: Metabolism
Uniprot ID: Q9HC16
