Product Description
anti- ARHGEF7 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons..
Immunogen: Rho guanine nucleotide exchange factor(GEF) 7
Synonyms: COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IP, WB
Recommended dilution: WB: 1:1000-1:4000; IP: 1:500-1:2000
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Image 4: PC-12 cells were subjected to SDS PAGE followed by western blot with FNab00564 (ARHGEF7 antibody) at dilution of 1:2000
Gene ID: 8874
Research Area: Metabolism
Uniprot ID: Q14155