Product Description
anti- ARL3 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins(GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit..
Immunogen: ADP-ribosylation factor-like 3
Synonyms: ARFL3
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab00576(ARL3 Antibody) at dilution of 1:200
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab00576(ARL3 antibody) at dilution of 1:1000
Gene ID: 403
Research Area: Metabolism
Uniprot ID: P36405