Product Description
anti- ARNT2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively..
Immunogen: aryl-hydrocarbon receptor nuclear translocator 2
Synonyms: BHLHE1, KIAA0307
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded human kidney using FNab00595(ARNT2 antibody) at dilution of 1:100
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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00595(ARNT2 antibody) at dilution of 1:1000
Gene ID: 9915
Research Area: Metabolism
Uniprot ID: Q9HBZ2