anti- ATG12 antibody

Product Description

anti- ATG12 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus..

Immunogen: ATG12 autophagy related 12 homolog(S. cerevisiae)

Synonyms: APG12, APG12L

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100

Image 1: Immunohistochemistry of paraffin-embedded human prostate cancer using FNab00667(ATG12 antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of PC3 cells using FNab00667 (ATF12 antibody) at dilution of 1:25.

Image 3:

Image 4: human bladder tissue were subjected to SDS PAGE followed by western blot with FNab00667(ATG12 antibody) at dilution of 1:500

Gene ID: 9140

Research Area: Metabolism

Uniprot ID: O94817