anti- ATG4C antibody

Product Description

anti- ATG4C antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation(By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms..

Immunogen: ATG4 autophagy related 4 homolog C(S. cerevisiae)

Synonyms: APG4C, AUTL1, AUTL3

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC, IF

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human heart using FNab00675(ATG4C antibody) at dilution of 1:50

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Image 4: mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab00675(ATG4C antibody) at dilution of 1:500

Gene ID: 84938

Research Area: Metabolism

Uniprot ID: Q96DT6