anti- ATP5A1 antibody

Product Description

anti- ATP5A1 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Mitochondrial membrane ATP synthase(F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1)-containing the extramembraneous catalytic core, and F(0)-containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites(By similarity)..

Immunogen: ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle

Synonyms: ATP5A, ATP5AL2, ATPM

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, IF, WB, FC

Recommended dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human heart using FNab00703(ATP5A1 antibody) at dilution of 1:50

Image 2: .

Image 3: IP Result of anti-ATP5A1 (IP: FNab00703, 5ug; Detection: FNab00703 1:500) with mouse heart tissue lysate 4000ug.

Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00703(ATP5A1 antibody) at dilution of 1:1000

Gene ID: 498

Research Area: Metabolism

Uniprot ID: P25705