anti- BBS9 antibody

Product Description

anti- BBS9 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization..

Immunogen: Bardet-Biedl syndrome 9

Synonyms: PTHB1

Reactivity: Human, Mouse

Tested Application: ELISA, IHC, IF, WB, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human liver using FNab00825(BBS9 antibody) at dilution of 1:50

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Image 4: mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab00825(BBS9 antibody) at dilution of 1:300

Gene ID: 27241

Research Area: Metabolism

Uniprot ID: Q3SYG4