Product Description
anti- BCOR antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4'(H3K4me3) and 'Lys-36'(H3K36me2)..
Immunogen: BCL6 co-repressor
Synonyms: KIAA1575
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500 - 1:2000
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Image 4: Hela cells were subjected to SDS PAGE followed by western blot with FNab00853(BCOR antibody) at dilution of 1:1000
Gene ID: 54880
Research Area: Metabolism
Uniprot ID: Q6W2J9