Euro
British Pound
US Dollar
Product Description
anti- BUB3 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule(K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome(APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1..
Immunogen: budding uninhibited by benzimidazoles 3 homolog(yeast)
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IF
Recommended dilution:
Image 1:
Image 2: .
Image 3:
Image 4:
Gene ID: 9184
Research Area: Metabolism
Uniprot ID: O43684
