anti- BVES antibody

Product Description

anti- BVES antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction(TJ) paracellular permeability barrier in epithelial cells(PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading(By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density(PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury..

Immunogen: blood vessel epicardial substance

Synonyms: POP1,

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human ovary tumor using FNab00992(BVES antibody) at dilution of 1:100

Image 2: .

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Image 4: mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab00992(BVES antibody) at dilution of 1:500

Gene ID: 11149

Research Area: Metabolism

Uniprot ID: Q8NE79