anti- C4BPB antibody

Product Description

anti- C4BPB antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants..

Immunogen: complement component 4 binding protein, beta

Synonyms: C4BP

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded mouse kidney using FNab01114(C4BPB antibody) at dilution of 1:100

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab01114(C4BPB antibody) at dilution of 1:1000

Gene ID: 725

Research Area: Metabolism

Uniprot ID: P20851