anti- CACNA1S antibody

Product Description

anti- CACNA1S antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting(L-type) calcium channels belong to the 'high-voltage activated'(HVA) group. They are blocked by dihydropyridines(DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA(omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA(omega-CTx-GVIA) and omega-agatoxin-IVA(omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle..

Immunogen: calcium channel, voltage-dependent, L type, alpha 1S subunit

Synonyms: CACH1, CACN1, CACNL1A3

Reactivity: Human

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human skeletal muscle slide using FNab01173(CACNA1S Antibody) at dilution of 1:50

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Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab01173(CACNA1S antibody) at dilution of 1:1000

Gene ID: 779

Research Area: Metabolism

Uniprot ID: Q13698