anti- CASP14 antibody

Product Description

anti- CASP14 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier..

Immunogen: CASP14

Synonyms: CASP14, ARCI12, caspase-14

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF

Recommended dilution: WB: 1:500 - 1:2000; IF: 1:50 - 1:200

Image 1:

Image 2: Immunofluorescent analysis of MCF-7 cells using FNab09900( CASP14 antibody) at dilution of 1:100..

Image 3:

Image 4: 293T cells were subjected to SDS PAGE followed by western blot with FNab09900( CASP14 antibody) at dilution of 1:1000

Gene ID: 23581

Research Area: Metabolism

Uniprot ID: P31944