anti- CBS antibody

Product Description

anti- CBS antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine(PubMed:23981774, PubMed:20506325, PubMed:23974653). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons(By similarity)..

Immunogen: cystathionine-beta-synthase

Synonyms: Beta thionase, CBS, cystathionine beta synthase, HIP4, Serine sulfhydrase

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF, IP

Recommended dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using FNab01327(CBS Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

Image 2: Immunofluorescent analysis of U2OS cells, using FNab01327(CBS Antibody) at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red)..

Image 3:

Image 4: mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab01327(CBS antibody) at dilution of 1:500

Gene ID: 875

Research Area: Metabolism

Uniprot ID: P35520