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Product Description
anti- CD86 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B..
Immunogen: CD86 molecule
Synonyms: Activation B7 2 antigen, B7 2, B70, BU63, CD28LG2, CD86, CD86 molecule, CTLA 4 counter receptor B7.2, FUN 1, LAB72
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB,IHC
Recommended dilution: WB: 1:200-1:2000; IHC: 1:50-1:500
Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01504(CD86 Antibody) at dilution of 1:200. heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01504(CD86 antibody) at dilution of 1:500
Gene ID: 942
Research Area: Metabolism
Uniprot ID: P42081
