anti- CHI3L1 antibody

Product Description

anti- CHI3L1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2(Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung..

Immunogen: chitinase 3-like 1(cartilage glycoprotein-39)

Synonyms: 39 kDa synovial protein, ASRT7, Cartilage glycoprotein 39, CGP 39, CHI3L1, Chitinase 3 like protein 1, GP 39, GP39, HC gp39, hCGP 39, HCGP 3P, YKL 40, YKL40, YYL 40

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC

Recommended dilution: IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human liver tissue using FNab01649(CHI3L1 antibody) at dilution of 1:100

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Gene ID: 1116

Research Area: Metabolism

Uniprot ID: P36222