anti- CLSTN1 antibody

Product Description

anti- CLSTN1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment(AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals(By similarity)..

Immunogen: calsyntenin 1

Synonyms: CS1, KIAA0911

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab01776(CLSTN1 antibody) at dilution of 1:600

Gene ID: 22883

Research Area: Metabolism

Uniprot ID: O94985