anti- CNOT7 antibody

Product Description

anti- CNOT7 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity..

Immunogen: CCR4-NOT transcription complex, subunit 7

Synonyms: CAF1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IP

Recommended dilution:

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Image 4: mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab01811(CNOT7 antibody) at dilution of 1:500

Gene ID: 29883

Research Area: Metabolism

Uniprot ID: Q9UIV1