anti- Collagen Type I antibody

Product Description

anti- Collagen Type I antibody is available at Gentaur for Next week Delivery.

Purification: protein A+G purified

Background: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene..

Immunogen: collagen, type I, alpha 2

Synonyms: Alpha 2 type I collagen, COL1A2, Collagen alpha 2(I) chain, Collagen Type I, collagen, type I, alpha 2, OI4

Reactivity: Human

Tested Application: ELISA, IHC

Recommended dilution: IHC: 1:2000 - 1:8000

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab09910( COL1A2 Antibody) at dilution of 1:5000

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Gene ID: 1278

Research Area: Metabolism

Uniprot ID: P08123