anti- COX6A1 antibody

Product Description

anti- COX6A1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented..

Immunogen: cytochrome c oxidase subunit VIa polypeptide 1

Synonyms: COX6AL

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:200 - 1:2000; IHC: 1:20 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human liver cancer using FNab01902(COX6A1 antibody) at dilution of 1:100

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Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab01902(COX6A1 antibody) at dilution of 1:1000

Gene ID: 1337

Research Area: Metabolism

Uniprot ID: P12074