anti- CXADR antibody

Product Description

anti- CXADR antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. (Microbial infection) Acts as a receptor for adenovirus type C(PubMed:9733828, PubMed:10666333, PubMed:12297051, PubMed:10567268). Acts as a receptor for Coxsackievirus B1 to B6(PubMed:14978041, PubMed:10814575)..

Immunogen: coxsackie virus and adenovirus receptor

Synonyms: CAR

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab02091(CXADR antibody) at dilution of 1:50

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Image 4: BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab02091(CXADR antibody) at dilution of 1:500

Gene ID: 1525

Research Area: Metabolism

Uniprot ID: P78310