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Product Description
anti- CYP1A1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms..
Immunogen: cytochrome P450, family 1, subfamily A, polypeptide 1
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded human esophageal cancer using FNab02147(CYP1A1 antibody) at dilution of 1:100
Image 2: .
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Image 4: mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with FNab02147(CYP1A1 antibody) at dilution of 1:1000
Gene ID: 1543
Research Area: Metabolism
Uniprot ID: P04798
