anti- Cytokeratin 18 antibody

Product Description

anti- Cytokeratin 18 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas..

Immunogen: keratin 18

Synonyms: CK 18, CYK18, Cytokeratin 18, K18, keratin 18, KRT18

Reactivity: Human

Tested Application: ELISA, WB, FC, IF, IHC

Recommended dilution: WB: 1:5000-1:50000; IHC: 1:600-1:2000; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab02206(KRT18 Antibody) at dilution of 1:200

Image 2: Immunofluorescent analysis of HepG2 cells using FNab02206 ( KRT18 Antibody) at dilution of 1:25 and Alexa Fluor 594-congugated AffiniPure Goat Anti-Mouse IgG(H+L).

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02206(KRT18 Antibody) at dilution of 1:20000

Gene ID:

Research Area: Metabolism

Uniprot ID: P05783