anti- DBI antibody

Product Description

anti- DBI antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene..

Immunogen: diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)

Synonyms: DBI, ACBD1, ACBP, CCK-RP, EP, acyl-CoA-binding protein

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human Lung cancer using FNab02256(DBI antibody) at dilution of 1:50

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Image 4: A431 cells were subjected to SDS PAGE followed by western blot with FNab02256(DBI antibody) at dilution of 1:1000

Gene ID: 1622

Research Area: Metabolism

Uniprot ID: P07108