anti- DNAJC10 antibody

Product Description

anti- DNAJC10 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation(ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress..

Immunogen: DnaJ(Hsp40) homolog, subfamily C, member 10

Synonyms: ERDJ5

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab02457(DNAJC10 antibody) at dilution of 1:100

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02457(DNAJC10 antibody) at dilution of 1:1500

Gene ID: 54431

Research Area: Metabolism

Uniprot ID: Q8IXB1