anti- DTX1 antibody

Product Description

anti- DTX1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity(By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB(Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1..

Immunogen: deltex homolog 1(Drosophila)

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IF, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab02553(DTX1 antibody) at dilution of 1:100

Image 2: .

Image 3:

Image 4:

Gene ID: 1840

Research Area: Metabolism

Uniprot ID: Q86Y01