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Product Description
anti- E2F1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters(PubMed:20176812)..
Immunogen: E2F transcription factor 1
Synonyms: RBBP3
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab02600(E2F1 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02600(E2F1 Antibody) at dilution of 1:300
Gene ID: 1869
Research Area: Metabolism
Uniprot ID: Q01094
