anti- EIF3D antibody

Product Description

anti- EIF3D antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2(PubMed:18056426)..

Immunogen: eukaryotic translation initiation factor 3, subunit D

Synonyms: EIF3S7

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:2000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human brain using FNab02705(EIF3D antibody) at dilution of 1:50

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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab02705(EIF3D antibody) at dilution of 1:1000

Gene ID: 8664

Research Area: Metabolism

Uniprot ID: O15371