anti- EIF3E antibody

Product Description

anti- EIF3E antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay(NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins..

Immunogen: eukaryotic translation initiation factor 3, subunit E

Synonyms: EIF3S6,

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab02707(EIF3E antibody) at dilution of 1:100

Image 2: .

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Image 4: rat lymph tissue were subjected to SDS PAGE followed by western blot with FNab02707(EIF3E antibody) at dilution of 1:100

Gene ID: 3646

Research Area: Metabolism

Uniprot ID: P60228