Product Description
anti- EIF3I antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation..
Immunogen: eukaryotic translation initiation factor 3, subunit I
Synonyms: EIF3S2, TRIP1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, IF, IP, WB, FC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab02710(EIF3I antibody) at dilution of 1:100
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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab02710(EIF3I antibody) at dilution of 1:1000
Gene ID: 8668
Research Area: Metabolism
Uniprot ID: Q13347