anti- EIF3J antibody

Product Description

anti- EIF3J antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl(A) site. It may regulate the interaction between the 43S PIC and mRNA..

Immunogen: eukaryotic translation initiation factor 3, subunit J

Synonyms: EIF3S1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab02711(EIF3J antibody) at dilution of 1:100

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02711(EIF3J antibody) at dilution of 1:500

Gene ID: 8669

Research Area: Metabolism

Uniprot ID: O75822