anti- EIF5A antibody

Product Description

anti- EIF5A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts..

Immunogen: eukaryotic translation initiation factor 5A

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human kidney using FNab02728(EIF5A antibody) at dilution of 1:100

Image 2: .

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02728(EIF5A antibody) at dilution of 1:1000

Gene ID: 1984

Research Area: Metabolism

Uniprot ID: P63241