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Product Description
anti- ELF4 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter(By similarity). Also transactivates the PRF1 promoter in natural killer(NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2(By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway..
Immunogen: E74-like factor 4(ets domain transcription factor)
Synonyms: ELFR,
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IP
Recommended dilution:
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Image 4: NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab02737(ELF4 antibody) at dilution of 1:1000
Gene ID: 2000
Research Area: Metabolism
Uniprot ID: Q99607
