anti- EPOR antibody

Product Description

anti- EPOR antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants..

Immunogen: erythropoietin receptor

Synonyms: EPO R, EPOR, erythropoietin receptor

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human prostate using FNab02816(EPOR antibody) at dilution of 1:100

Image 2: Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HepG2 cells using FNab02816 ( EPOR Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Image 3: IP Result of anti-EPOR (IP: FNab02816, 4ug; Detection: FNab02816 1:500) with HepG2 cells lysate 1920ug.

Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab02816( EPOR Antibody) at dilution of 1:1000

Gene ID: 2057

Research Area: Metabolism

Uniprot ID: P19235