anti- ERCC2 antibody

Product Description

anti- ERCC2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair(NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase(CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers..

Immunogen: excision repair cross-complementing rodent repair deficiency, complementation group 2

Synonyms: XPD, XPDC

Reactivity: Human

Tested Application: ELISA, WB, IHC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human lymphoma using FNab02833(ERCC2 antibody) at dilution of 1:100

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab02833(ERCC2 antibody) at dilution of 1:500

Gene ID: 2068

Research Area: Metabolism

Uniprot ID: P18074